Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates

As genetic code expansion advances beyond l-α-amino acids to backbone modifications and new polymerization chemistries, delineating what substrates the ribosome can accommodate remains a challenge. The Escherichia coli ribosome tolerates non-l-α-amino acids in vitro, but few structural insights that...

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Detalles Bibliográficos
Autores principales: Watson, Zoe L., Knudson, Isaac J., Ward, Fred R., Miller, Scott J., Cate, Jamie H. D., Schepartz, Alanna, Abramyan, Ara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322701/
https://www.ncbi.nlm.nih.gov/pubmed/37308707
http://dx.doi.org/10.1038/s41557-023-01226-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322701/
https://www.ncbi.nlm.nih.gov/pubmed/37308707
http://dx.doi.org/10.1038/s41557-023-01226-w

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