Heritable transcriptional defects from aberrations of nuclear architecture

Transcriptional heterogeneity due to plasticity of the epigenetic state of chromatin contributes to tumour evolution, metastasis and drug resistance(1–3). However, the mechanisms that cause this epigenetic variation are incompletely understood. Here we identify micronuclei and chromosome bridges, ab...

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Detalles Bibliográficos
Autores principales: Papathanasiou, Stamatis, Mynhier, Nikos A., Liu, Shiwei, Brunette, Gregory, Stokasimov, Ema, Jacob, Etai, Li, Lanting, Comenho, Caroline, van Steensel, Bas, Buenrostro, Jason D., Zhang, Cheng-Zhong, Pellman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322708/
https://www.ncbi.nlm.nih.gov/pubmed/37286600
http://dx.doi.org/10.1038/s41586-023-06157-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322708/
https://www.ncbi.nlm.nih.gov/pubmed/37286600
http://dx.doi.org/10.1038/s41586-023-06157-7

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