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Origin and evolutionary malleability of T cell receptor α diversity

Lymphocytes of vertebrate adaptive immune systems acquired the capability to assemble, from split genes in the germline, billions of functional antigen receptors(1–3). These receptors show specificity; unlike the broadly tuned receptors of the innate system, antibodies (Ig) expressed by B cells, for...

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Detalles Bibliográficos
Autores principales: Giorgetti, Orlando B., O’Meara, Connor P., Schorpp, Michael, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322711/
https://www.ncbi.nlm.nih.gov/pubmed/37344590
http://dx.doi.org/10.1038/s41586-023-06218-x