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Origin and evolutionary malleability of T cell receptor α diversity
Lymphocytes of vertebrate adaptive immune systems acquired the capability to assemble, from split genes in the germline, billions of functional antigen receptors(1–3). These receptors show specificity; unlike the broadly tuned receptors of the innate system, antibodies (Ig) expressed by B cells, for...
Autores principales: | Giorgetti, Orlando B., O’Meara, Connor P., Schorpp, Michael, Boehm, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322711/ https://www.ncbi.nlm.nih.gov/pubmed/37344590 http://dx.doi.org/10.1038/s41586-023-06218-x |
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