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Transient regulatory-T-cell interruption promotes skin-resident memory T cells mediated tumor protection
Most cancer immunotherapy approaches aim to stimulate cytotoxic CD8(+) T lymphocytes to reject tumor cells. Due to the tumor-mediated suppressive micro-environment, of which the major contributor is regulatory T cells (Tregs), promising preclinical approaches were disappointing in clinical settings....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322828/ https://www.ncbi.nlm.nih.gov/pubmed/37407600 http://dx.doi.org/10.1038/s41598-023-36884-w |