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Transient regulatory-T-cell interruption promotes skin-resident memory T cells mediated tumor protection

Most cancer immunotherapy approaches aim to stimulate cytotoxic CD8(+) T lymphocytes to reject tumor cells. Due to the tumor-mediated suppressive micro-environment, of which the major contributor is regulatory T cells (Tregs), promising preclinical approaches were disappointing in clinical settings....

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Detalles Bibliográficos
Autores principales: Zhao, Shushu, Wu, Shuting, Jiang, Sheng, Zhou, Xiaoyu, Zhao, Gan, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322828/
https://www.ncbi.nlm.nih.gov/pubmed/37407600
http://dx.doi.org/10.1038/s41598-023-36884-w