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Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses
Extrafollicular plasmablast responses (EFRs) are considered to generate antibodies of low affinity that offer little protection from infections. Paradoxically, high avidity antigen-B cell receptor engagement is thought to be the main driver of B cell differentiation, whether in EFRs or slower-develo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322839/ https://www.ncbi.nlm.nih.gov/pubmed/37407556 http://dx.doi.org/10.1038/s41467-023-39734-5 |