RAS-independent ERK activation by constitutively active KSR3 in non-chordate metazoa

During early development of the sea urchin embryo, activation of ERK signalling in mesodermal precursors is not triggered by extracellular RTK ligands but by a cell-autonomous, RAS-independent mechanism that was not understood. We discovered that in these cells, ERK signalling is activated through t...

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Detalles Bibliográficos
Autores principales: Chessel, Aline, De Crozé, Noémie, Molina, Maria Dolores, Taberner, Laura, Dru, Philippe, Martin, Luc, Lepage, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322840/
https://www.ncbi.nlm.nih.gov/pubmed/37407549
http://dx.doi.org/10.1038/s41467-023-39606-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322840/
https://www.ncbi.nlm.nih.gov/pubmed/37407549
http://dx.doi.org/10.1038/s41467-023-39606-y

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