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Galectin-9 has non-apoptotic cytotoxic activity toward acute myeloid leukemia independent of cytarabine resistance

Acute myeloid leukemia (AML) is a malignancy still associated with poor survival rates, among others, due to frequent occurrence of therapy-resistant relapse after standard-of-care treatment with cytarabine (AraC). AraC triggers apoptotic cell death, a type of cell death to which AML cells often bec...

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Detalles Bibliográficos
Autores principales: Choukrani, Ghizlane, Visser, Nienke, Ustyanovska Avtenyuk, Natasha, Olthuis, Mirjam, Marsman, Glenn, Ammatuna, Emanuele, Lourens, Harm Jan, Niki, Toshiro, Huls, Gerwin, Bremer, Edwin, Wiersma, Valerie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322858/
https://www.ncbi.nlm.nih.gov/pubmed/37407572
http://dx.doi.org/10.1038/s41420-023-01515-w