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Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc pathway

Increased use of benzodiazepines in adolescents have been reported, with alprazolam (ALP) being the most abused. Drug abuse during adolescence can induce changes with lasting consequences. This study investigated the neurobiological consequences of ALP exposure during adolescence in C57BL/6J male mi...

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Detalles Bibliográficos
Autores principales: Cardona-Acosta, Astrid M., Sial, Omar K., Parise, Lyonna F., Gnecco, Tamara, Enriquez Marti, Giselle, Bolaños-Guzmán, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322866/
https://www.ncbi.nlm.nih.gov/pubmed/37407659
http://dx.doi.org/10.1038/s41598-023-37696-8