Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress

Drug-induced liver injury (DILI) is the leading cause of acute liver failure (ALF). Continuous and prolonged hepatic cellular oxidative stress and liver inflammatory stimuli are key signatures of DILI. DEAD-box helicase 3, X-linked (DDX3X) is a central regulator in pro-survival stress granule (SG) a...

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Detalles Bibliográficos
Autores principales: Luo, Tingting, Yang, Suzhen, Zhao, Tianming, Zhu, Hanlong, Chen, Chunyan, Shi, Xiaoxiao, Chen, Di, Wang, Kai, Jiang, Kang, Xu, Dan, Cheng, Ming, Li, Juan, Li, Wenting, Xu, Weijun, Zhou, Lin, Jiang, Mingzuo, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322869/
https://www.ncbi.nlm.nih.gov/pubmed/37407573
http://dx.doi.org/10.1038/s41419-023-05913-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322869/
https://www.ncbi.nlm.nih.gov/pubmed/37407573
http://dx.doi.org/10.1038/s41419-023-05913-x

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