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Generation of B-cell-based cellular vaccine for cancer in murine models
A B-cell-based cellular vaccine (B(Vax)), produced from 4-1BBL(+) B cells, can select tumor-specific B cells that, upon ex vivo culture, can generate tumor-specific antibodies and activate T cells. Here, we present a protocol to generate a B-cell-based vaccine in a CT2A orthotopic glioma murine mode...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322876/ https://www.ncbi.nlm.nih.gov/pubmed/37083319 http://dx.doi.org/10.1016/j.xpro.2023.102219 |