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Generation of B-cell-based cellular vaccine for cancer in murine models

A B-cell-based cellular vaccine (B(Vax)), produced from 4-1BBL(+) B cells, can select tumor-specific B cells that, upon ex vivo culture, can generate tumor-specific antibodies and activate T cells. Here, we present a protocol to generate a B-cell-based vaccine in a CT2A orthotopic glioma murine mode...

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Detalles Bibliográficos
Autores principales: Hou, David, Katz, Joshua L., Lee-Chang, Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322876/
https://www.ncbi.nlm.nih.gov/pubmed/37083319
http://dx.doi.org/10.1016/j.xpro.2023.102219