Novel aminopyridazine derivative of minaprine modified by radiolysis presents potent anti-inflammatory effects in LPS-stimulated RAW 264.7 and DH82 macrophage cells

Radiation molecularly transforms naturally occurring products by inducing the methoxylation, hydroxylation, and alkylation of parent compounds, thereby affecting the anti-inflammatory capacities of those compounds. Minaprine (1) modified by ionizing radiation generated the novel hydroxymethylation h...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Gyeong Han, Lee, Hanui, Woo, So-Yeun, Lee, Hong-Ki, Chung, Byung Yeoup, Bai, Hyoung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322889/
https://www.ncbi.nlm.nih.gov/pubmed/37407652
http://dx.doi.org/10.1038/s41598-023-37812-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322889/
https://www.ncbi.nlm.nih.gov/pubmed/37407652
http://dx.doi.org/10.1038/s41598-023-37812-8

Ejemplares similares