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Profiling of basal and ligand-dependent GPCR activities by means of a polyvalent cell-based high-throughput platform
Representing the most attractive and successful druggable receptors of the proteome, GPCRs regulate a myriad of physiological and pathophysiological functions. Although over half of present pharmaceuticals target GPCRs, the advancement of drug discovery is hampered by a lack of adequate screening to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322906/ https://www.ncbi.nlm.nih.gov/pubmed/37407564 http://dx.doi.org/10.1038/s41467-023-39132-x |