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Xrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes
Mammalian oocytes spend most of their life in a unique state of cell cycle arrest at meiotic prophase I, during which time they are exposed to countless DNA-damaging events. Recent studies have shown that DNA double-strand break repair occurs predominantly via the homologous recombination (HR) pathw...
Autores principales: | Cai, Xuebi, Stringer, Jessica M., Zerafa, Nadeen, Carroll, John, Hutt, Karla J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322932/ https://www.ncbi.nlm.nih.gov/pubmed/37407587 http://dx.doi.org/10.1038/s41419-023-05886-x |
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