Pharmacokinetics and Drug–Drug Interaction of Ocedurenone (KBP-5074) in vitro and in vivo

BACKGROUND AND OBJECTIVES: Ocedurenone (KBP-5074) is a novel nonsteroidal mineralocorticoid receptor antagonist that has demonstrated safety and efficacy in clinical trials in patients with uncontrolled hypertension and stage 3b/4 chronic kidney disease. This study evaluated the involvement of cytoc...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Liu, Jinrong, Tan, Xiaojuan, Yang, Fred, McCabe, James, Zhang, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322960/
https://www.ncbi.nlm.nih.gov/pubmed/37357226
http://dx.doi.org/10.1007/s13318-023-00837-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322960/
https://www.ncbi.nlm.nih.gov/pubmed/37357226
http://dx.doi.org/10.1007/s13318-023-00837-5

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