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Pharmacokinetics and Drug–Drug Interaction of Ocedurenone (KBP-5074) in vitro and in vivo
BACKGROUND AND OBJECTIVES: Ocedurenone (KBP-5074) is a novel nonsteroidal mineralocorticoid receptor antagonist that has demonstrated safety and efficacy in clinical trials in patients with uncontrolled hypertension and stage 3b/4 chronic kidney disease. This study evaluated the involvement of cytoc...
Autores principales: | Wang, Ping, Liu, Jinrong, Tan, Xiaojuan, Yang, Fred, McCabe, James, Zhang, Jay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322960/ https://www.ncbi.nlm.nih.gov/pubmed/37357226 http://dx.doi.org/10.1007/s13318-023-00837-5 |
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