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Modular synthesis of clickable peptides via late-stage maleimidation on C(7)-H tryptophan
Cyclic peptides have attracted tremendous attention in the pharmaceutical industry owing to their excellent cell penetrability, stability, thermostability, and drug-like properties. However, the currently available facile methodologies for creating such peptides are rather limited. Herein, we report...
Autores principales: | Wang, Peng, Liu, Jiang, Zhu, Xiaomei, Kenry, Yan, Zhengqing, Yan, Jiahui, Jiang, Jitong, Fu, Manlin, Ge, Jingyan, Zhu, Qing, Zheng, Yuguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322970/ https://www.ncbi.nlm.nih.gov/pubmed/37407547 http://dx.doi.org/10.1038/s41467-023-39703-y |
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