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A co-culture model system to quantify antibody-dependent cellular cytotoxicity in human breast cancer cells using an engineered natural killer cell line

Current protocols measure antibody-dependent cellular cytotoxicity (ADCC) in vitro using peripheral blood mononuclear cells (PBMCs), but isolation and variability among donors limit the viability and reproducibility of this approach. Here, we present a standardized co-culture model system to quantif...

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Detalles Bibliográficos
Autores principales: Vincken, Roos, Ruiz-Saenz, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323021/
https://www.ncbi.nlm.nih.gov/pubmed/37071532
http://dx.doi.org/10.1016/j.xpro.2023.102224