The histone demethylase Utx controls CD8 (+) T‐cell‐dependent antitumor immunity via epigenetic regulation of the effector function

CD8(+) T cells play a central role in antitumor immune responses. Epigenetic gene regulation is essential to acquire the effector function of CD8(+) T cells. However, the role of Utx, a demethylase of histone H3K27, in antitumor immunity remains unclear. In this study, we examined the roles of Utx i...

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Detalles Bibliográficos
Autores principales: Noda, Haruna, Suzuki, Junpei, Matsuoka, Yuko, Matsumoto, Akira, Kuwahara, Makoto, Kamei, Yoshiaki, Takada, Yasutsugu, Yamashita, Masakatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323087/
https://www.ncbi.nlm.nih.gov/pubmed/37068788
http://dx.doi.org/10.1111/cas.15814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323087/
https://www.ncbi.nlm.nih.gov/pubmed/37068788
http://dx.doi.org/10.1111/cas.15814

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