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Combination therapy of DKK1 inhibition and NKG2D chimeric antigen receptor T cells for the treatment of gastric cancer

Despite the successful application of chimeric antigen receptor (CAR)‐T cell therapy in hematological malignancies, the treatment efficacy in solid tumors remains unsatisfactory, largely due to the highly immunosuppressive tumor microenvironment and low density of specific tumor antigens. Natural ki...

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Detalles Bibliográficos
Autores principales: Zhang, Yipeng, Liang, Kaijie, Zhou, Xiaoyu, Zhang, Xin, Xu, Hui, Dai, Hongjiu, Song, Xueru, Yang, Xueyi, Liu, Baorui, Shi, Tao, Wei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323088/
https://www.ncbi.nlm.nih.gov/pubmed/37151176
http://dx.doi.org/10.1111/cas.15828