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Invalidity of, and alternative to, the linear quadratic model as a predictive model for postirradiation cell survival
The linear quadratic (LQ) model has been the dominant tool in preclinical radiobiological modeling of cell survival as a function of dose. However, as a second‐order polynomial approximation, it suffers from two well‐known pitfalls: nonmonotonic behavior and poor extrapolation. This study examined t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323099/ https://www.ncbi.nlm.nih.gov/pubmed/36946242 http://dx.doi.org/10.1111/cas.15796 |