MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5

MLK4, a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family, has been implicated in cancer progression. However, its role in lung adenocarcinoma has not been characterized. Here, we showed that MLK4 was overexpressed in a significant subset of lung adenocarcinoma, associated...

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Detalles Bibliográficos
Autores principales: Cheung, Alvin Ho-Kwan, Wong, Kit-Yee, Liu, Xiaoli, Ji, Fenfen, Hui, Chris Ho-Lam, Zhang, Yihan, Kwan, Johnny Sheung-Him, Chen, Bonan, Dong, Yujuan, Lung, Raymond Wai-Ming, Yu, Jun, Lo, Kwok Wai, Wong, Chi Chun, Kang, Wei, To, Ka-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323122/
https://www.ncbi.nlm.nih.gov/pubmed/37407566
http://dx.doi.org/10.1038/s41389-023-00478-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323122/
https://www.ncbi.nlm.nih.gov/pubmed/37407566
http://dx.doi.org/10.1038/s41389-023-00478-y

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