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SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion

INTRODUCTION: Virus-like particles (VLPs) are similar in size and shape to their respective viruses, but free of viral genetic material. This makes VLP-based vaccines incapable of causing infection, but still effective in mounting immune responses. Noro-VLPs consist of 180 copies of the VP1 capsid p...

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Detalles Bibliográficos
Autores principales: Lampinen, Vili, Gröhn, Stina, Soppela, Saana, Blazevic, Vesna, Hytönen, Vesa P., Hankaniemi, Minna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323135/
https://www.ncbi.nlm.nih.gov/pubmed/37424789
http://dx.doi.org/10.3389/fcimb.2023.1216364