Viewpoint: spinocerebellar ataxias as diseases of Purkinje cell dysfunction rather than Purkinje cell loss

Spinocerebellar ataxias (SCAs) are a group of hereditary neurodegenerative diseases mostly affecting cerebellar Purkinje cells caused by a wide variety of different mutations. One subtype, SCA14, is caused by mutations of Protein Kinase C gamma (PKCγ), the dominant PKC isoform present in Purkinje ce...

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Detalles Bibliográficos
Autores principales: Kapfhammer, Josef P., Shimobayashi, Etsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323145/
https://www.ncbi.nlm.nih.gov/pubmed/37426070
http://dx.doi.org/10.3389/fnmol.2023.1182431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323145/
https://www.ncbi.nlm.nih.gov/pubmed/37426070
http://dx.doi.org/10.3389/fnmol.2023.1182431

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