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Preservation solution Custodiol containing human alpha-1-antitrypsin improves graft recovery after prolonged cold ischemic storage in a rat model of heart transplantation

INTRODUCTION: The shortage of available donor hearts and the risk of ischemia/reperfusion injury restrict heart transplantation (HTX). Alpha-1-antitrypsin (AAT), a well-characterized inhibitor of neutrophil serine protease, is used in augmentation therapy to treat emphysema due to severe AAT deficie...

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Detalles Bibliográficos
Autores principales: Korkmaz-Icöz, Sevil, Abulizi, Sophia, Li, Kunsheng, Korkmaz, Brice, Georgevici, Adrian-Iustin, Sayour, Alex Ali, Loganathan, Sivakkanan, Canoglu, Hansa, Karck, Matthias, Szabó, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323193/
https://www.ncbi.nlm.nih.gov/pubmed/37426668
http://dx.doi.org/10.3389/fimmu.2023.1155343