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Defining developmental trajectories of prosensory cells in human inner ear organoids at single-cell resolution

The inner ear sensory epithelia contain mechanosensitive hair cells and supporting cells. Both cell types arise from SOX2-expressing prosensory cells, but the mechanisms underlying the diversification of these cell lineages remain unclear. To determine the transcriptional trajectory of prosensory ce...

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Detalles Bibliográficos
Autores principales: Ueda, Yoshitomo, Nakamura, Takashi, Nie, Jing, Solivais, Alexander J., Hoffman, John R., Daye, Becca J., Hashino, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323240/
https://www.ncbi.nlm.nih.gov/pubmed/37381908
http://dx.doi.org/10.1242/dev.201071