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Microtubule binding of the human augmin complex is directly controlled by importins and Ran-GTP

Mitotic spindle assembly during cell division is a highly regulated process. Ran-GTP produced around chromosomes controls the activity of a multitude of spindle assembly factors by releasing them from inhibitory interaction with importins. A major consequence of Ran-GTP regulation is the local stimu...

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Detalles Bibliográficos
Autores principales: Ustinova, Kseniya, Ruhnow, Felix, Gili, Maria, Surrey, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323247/
https://www.ncbi.nlm.nih.gov/pubmed/37357828
http://dx.doi.org/10.1242/jcs.261096