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Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma

OBJECTIVE: Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, liquid biopsy of primary intramedullary astrocytoma was rarely reported. Given the distinct genomic profiles between primary intramedullary glioma and intracran...

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Detalles Bibliográficos
Autores principales: Cheng, Lei, Duan, Wanru, Guan, Jian, Wang, Kai, Liu, Zhenlei, Wang, Xingwen, Wang, Zuowei, Wu, Hao, Chen, Zan, Jian, Fengzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Spinal Neurosurgery Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323353/
https://www.ncbi.nlm.nih.gov/pubmed/37401089
http://dx.doi.org/10.14245/ns.2346210.105