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pncA Large Deletion is the Characteristic of Pyrazinamide-Resistant Mycobacterium tuberculosis belonging to the East Asian Lineage

BACKGROUND: Pyrazinamide (PZA) is often used as an add-on agent in the treatment of multidrug-resistant tuberculosis, regardless of phenotypic drug susceptibility testing (pDST) results. However, evaluating the effectiveness of PZA is challenging because of its low pH activity, which can result in u...

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Detalles Bibliográficos
Autores principales: Kim, Na Yung, Kim, Do Young, Chu, Jiyon, Jung, Seung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases; Korean Society for Antimicrobial Therapy; The Korean Society for AIDS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323538/
https://www.ncbi.nlm.nih.gov/pubmed/37407242
http://dx.doi.org/10.3947/ic.2023.0037