Epithelial-mesenchymal transition is associated with osteopontin-induced EGFR‑TKI resistance in EGFR mutant non-small cell lung cancer

BACKGROUND: Resistance restricts the long-term therapeutic efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in the treatment of non-small cell lung cancer (NSCLC) with positive EGFR mutations. The present study sought to identify the potential protein osteopontin (...

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Detalles Bibliográficos
Autores principales: Chen, Junjie, Shi, Lin, Qian, Yao, Jin, Yi, Dong, Nian, Chen, Chengshui, Wang, Beibei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323565/
https://www.ncbi.nlm.nih.gov/pubmed/37426126
http://dx.doi.org/10.21037/jtd-23-818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323565/
https://www.ncbi.nlm.nih.gov/pubmed/37426126
http://dx.doi.org/10.21037/jtd-23-818

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