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Remodeling Serine Synthesis and Metabolism via Nanoparticles (NPs)‐Mediated CFL1 Silencing to Enhance the Sensitivity of Hepatocellular Carcinoma to Sorafenib

Tyrosine kinase inhibitors represented by sorafenib are the first‐line treatment for hepatocellular carcinoma (HCC), but the low response rate of HCC patient has become a clinical pain‐point. Emerging evidences have revealed that metabolic reprogramming plays an important role in regulating the sens...

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Detalles Bibliográficos
Autores principales: Li, Senlin, Xu, Lei, Wu, Guo, Huang, Ziqi, Huang, Linzhuo, Zhang, Fengqian, Wei, Chunfang, Shen, Qian, Li, Rong, Zhang, Lei, Xu, Xiaoding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323624/
https://www.ncbi.nlm.nih.gov/pubmed/37203277
http://dx.doi.org/10.1002/advs.202207118