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Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling

Parathyroid carcinoma (PC) is an ultra‐rare malignancy with a high risk of recurrence after surgery. Tumour‐directed systemic treatments for PC are not established. We used whole‐genome and RNA sequencing in four patients with advanced PC to identify molecular alterations that could guide clinical m...

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Detalles Bibliográficos
Autores principales: Teleanu, Maria‐Veronica, Fuss, Carmina T., Paramasivam, Nagarajan, Pirmann, Sebastian, Mock, Andreas, Terkamp, Christoph, Kircher, Stefan, Landwehr, Laura‐Sophie, Lenschow, Christina, Schlegel, Nicolas, Stenzinger, Albrecht, Jahn, Arne, Fassnacht, Martin, Glimm, Hanno, Hübschmann, Daniel, Fröhling, Stefan, Kroiss, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323885/
https://www.ncbi.nlm.nih.gov/pubmed/36808802
http://dx.doi.org/10.1002/1878-0261.13398