Hypoxia‐mediated regulation of DDX5 through decreased chromatin accessibility and post‐translational targeting restricts R‐loop accumulation

Local hypoxia occurs in most solid tumors and is associated with aggressive disease and therapy resistance. Widespread changes in gene expression play a critical role in the biological response to hypoxia. However, most research has focused on hypoxia‐inducible genes as opposed to those that are dec...

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Detalles Bibliográficos
Autores principales: Leszczynska, Katarzyna B., Dzwigonska, Monika, Estephan, Hala, Moehlenbrink, Jutta, Bowler, Elizabeth, Giaccia, Amato J., Mieczkowski, Jakub, Kaminska, Bozena, Hammond, Ester M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323886/
https://www.ncbi.nlm.nih.gov/pubmed/37013907
http://dx.doi.org/10.1002/1878-0261.13431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323886/
https://www.ncbi.nlm.nih.gov/pubmed/37013907
http://dx.doi.org/10.1002/1878-0261.13431

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