MicroRNA 483‐3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis

In colorectal cancer, the mechanisms underlying tumor aggressiveness require further elucidation. Taking advantage of a large panel of human metastatic colorectal cancer xenografts and matched stem‐like cell cultures (m‐colospheres), here we show that the overexpression of microRNA 483‐3p (miRNA‐483...

Descripción completa

Detalles Bibliográficos
Autores principales: Candiello, Ermes, Reato, Gigliola, Verginelli, Federica, Gambardella, Gennaro, D′Ambrosio, Antonio, Calandra, Noemi, Orzan, Francesca, Iuliano, Antonella, Albano, Raffaella, Sassi, Francesco, Luraghi, Paolo, Comoglio, Paolo M., Bertotti, Andrea, Trusolino, Livio, Boccaccio, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
https://www.ncbi.nlm.nih.gov/pubmed/36862005
http://dx.doi.org/10.1002/1878-0261.13408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
https://www.ncbi.nlm.nih.gov/pubmed/36862005
http://dx.doi.org/10.1002/1878-0261.13408

Ejemplares similares