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DNA-Compatible Conditions for the Formation of N-Methyl Peptide Bonds
[Image: see text] DNA-encoded libraries (DELs) are a powerful platform in drug discovery. Peptides have unique properties that make them attractive pharmaceutical candidates. N-methylation of the peptide backbone can confer beneficial properties such as increased proteolytic stability and membrane p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323948/ https://www.ncbi.nlm.nih.gov/pubmed/37426286 http://dx.doi.org/10.1021/acsomega.3c00576 |