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Multiple Fibroblast Subtypes Contribute to Matrix Deposition in Pulmonary Fibrosis

Progressive pulmonary fibrosis results from a dysfunctional tissue repair response and is characterized by fibroblast proliferation, activation, and invasion and extracellular matrix accumulation. Lung fibroblast heterogeneity is well recognized. With single-cell RNA sequencing, fibroblast subtypes...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Dai, Kristy, Zhang, Xuexi, Huang, Guanling, Lynn, Heather, Rabata, Anas, Liang, Jiurong, Noble, Paul W., Jiang, Dianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324043/
https://www.ncbi.nlm.nih.gov/pubmed/36927333
http://dx.doi.org/10.1165/rcmb.2022-0292OC