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Multiple Fibroblast Subtypes Contribute to Matrix Deposition in Pulmonary Fibrosis
Progressive pulmonary fibrosis results from a dysfunctional tissue repair response and is characterized by fibroblast proliferation, activation, and invasion and extracellular matrix accumulation. Lung fibroblast heterogeneity is well recognized. With single-cell RNA sequencing, fibroblast subtypes...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324043/ https://www.ncbi.nlm.nih.gov/pubmed/36927333 http://dx.doi.org/10.1165/rcmb.2022-0292OC |