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Comparative Saturation Binding Analysis of (64)Cu-Labeled Somatostatin Analogues Using Cell Homogenates and Intact Cells

[Image: see text] The development of novel ligands for G-protein-coupled receptors (GPCRs) typically entails the characterization of their binding affinity, which is often performed with radioligands in a competition or saturation binding assay format. Since GPCRs are transmembrane proteins, recepto...

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Detalles Bibliográficos
Autores principales: Ullrich, Martin, Brandt, Florian, Löser, Reik, Pietzsch, Jens, Wodtke, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324063/
https://www.ncbi.nlm.nih.gov/pubmed/37426243
http://dx.doi.org/10.1021/acsomega.3c02755