Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

In the past 25 years, the prevalence of Parkinson’s disease (PD) has nearly doubled. Age remains the primary risk factor for PD and as the global aging population increases this trend is predicted to continue. Even when treated with levodopa, the gold standard dopamine (DA) replacement therapy, indi...

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Detalles Bibliográficos
Autores principales: Caulfield, Margaret E., Werp, Molly J. Vander, Stancati, Jennifer A., Collier, Timothy J., Sortwell, Caryl E., Sandoval, Ivette M., Manfredsson, Fredric P., Steece-Collier, Kathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324103/
https://www.ncbi.nlm.nih.gov/pubmed/37001610
http://dx.doi.org/10.1016/j.nbd.2023.106111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324103/
https://www.ncbi.nlm.nih.gov/pubmed/37001610
http://dx.doi.org/10.1016/j.nbd.2023.106111

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