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MOKPE: drug–target interaction prediction via manifold optimization based kernel preserving embedding

BACKGROUND: In many applications of bioinformatics, data stem from distinct heterogeneous sources. One of the well-known examples is the identification of drug–target interactions (DTIs), which is of significant importance in drug discovery. In this paper, we propose a novel framework, manifold opti...

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Detalles Bibliográficos
Autores principales: Binatlı, Oğuz C., Gönen, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324162/
https://www.ncbi.nlm.nih.gov/pubmed/37407927
http://dx.doi.org/10.1186/s12859-023-05401-1