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VGAEDTI: drug-target interaction prediction based on variational inference and graph autoencoder

MOTIVATION: Accurate identification of Drug-Target Interactions (DTIs) plays a crucial role in many stages of drug development and drug repurposing. (i) Traditional methods do not consider the use of multi-source data and do not consider the complex relationship between data sources. (ii) How to bet...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Feng, Yinfei, Wu, Mengjie, Deng, Zengqian, Wang, Shudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324201/
https://www.ncbi.nlm.nih.gov/pubmed/37415176
http://dx.doi.org/10.1186/s12859-023-05387-w