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Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure

BACKGROUND: Sepsis and associated organ failures confer substantial morbidity and mortality. Xanthine oxidoreductase (XOR) is implicated in the development of tissue oxidative damage in a wide variety of respiratory and cardiovascular disorders including sepsis and sepsis-associated acute respirator...

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Detalles Bibliográficos
Autores principales: Gao, Li, Rafaels, Nicholas, Dudenkov, Tanda M., Damarla, Mahendra, Damico, Rachel, Maloney, James P., Moss, Marc, Martin, Greg S., Sevransky, Jonathan, Shanholtz, Carl, Herr, Dan L., Garcia, Joe G.N., Hernandez-Beeftink, Tamara, Villar, Jesús, Flores, Carlos, Beaty, Terri H., Brower, Roy, Hassoun, Paul M., Barnes, Kathleen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324226/
https://www.ncbi.nlm.nih.gov/pubmed/37415141
http://dx.doi.org/10.1186/s12931-023-02481-8