Fibrin glue delivery system containing rhein ameliorates intervertebral disc degeneration by anti-inflammatory efficacy

PURPOSE: To construct an injectable, sustained-release fibrin gel containing rhein to solve the problem of low bioavailability of rhein, and observe its efficacy in the treatment of intervertebral disc degeneration. METHODS: The fibrin gel containing rhein was first synthesized in advance. Subsequen...

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Detalles Bibliográficos
Autores principales: Bao, Jianhang, Gao, Wenshuo, Zhang, Wei, Wang, Dong, Pan, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324239/
https://www.ncbi.nlm.nih.gov/pubmed/37415165
http://dx.doi.org/10.1186/s13018-023-03961-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324239/
https://www.ncbi.nlm.nih.gov/pubmed/37415165
http://dx.doi.org/10.1186/s13018-023-03961-9

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