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Fibrin glue delivery system containing rhein ameliorates intervertebral disc degeneration by anti-inflammatory efficacy

PURPOSE: To construct an injectable, sustained-release fibrin gel containing rhein to solve the problem of low bioavailability of rhein, and observe its efficacy in the treatment of intervertebral disc degeneration. METHODS: The fibrin gel containing rhein was first synthesized in advance. Subsequen...

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Detalles Bibliográficos
Autores principales:	Bao, Jianhang, Gao, Wenshuo, Zhang, Wei, Wang, Dong, Pan, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324239/ https://www.ncbi.nlm.nih.gov/pubmed/37415165 http://dx.doi.org/10.1186/s13018-023-03961-9

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