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PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer
BACKGROUND: Prostate cancer (PCa) is a prevalent malignant disease affecting a significant number of males globally. Elevated expression of the Bloom’s syndrome protein (BLM) helicase has emerged as a promising cancer biomarker, being associated with the onset and progression of PCa. Nevertheless, t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324254/ https://www.ncbi.nlm.nih.gov/pubmed/37415147 http://dx.doi.org/10.1186/s12967-023-04288-z |