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PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer

BACKGROUND: Prostate cancer (PCa) is a prevalent malignant disease affecting a significant number of males globally. Elevated expression of the Bloom’s syndrome protein (BLM) helicase has emerged as a promising cancer biomarker, being associated with the onset and progression of PCa. Nevertheless, t...

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Detalles Bibliográficos
Autores principales: Huang, Mengqiu, Chen, Lin, Guo, Yingchu, Ruan, Yong, Xu, Houqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324254/
https://www.ncbi.nlm.nih.gov/pubmed/37415147
http://dx.doi.org/10.1186/s12967-023-04288-z