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Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds

[Image: see text] Three peptides comprising mono-, di-, and tri-fluoroethylglycine (MfeGly, DfeGly, and TfeGly) residues alternating with lysine were digested by readily available proteases (elastase, bromelain, trypsin, and proteinase K). The degree of degradation depended on the enzyme employed an...

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Detalles Bibliográficos
Autores principales: Khan, Mohd Faheem, Chowdhary, Suvrat, Koksch, Beate, Murphy, Cormac D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324308/
https://www.ncbi.nlm.nih.gov/pubmed/37341426
http://dx.doi.org/10.1021/acs.est.3c01240