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Upregulation of Wnt2b exerts neuroprotective effect by alleviating mitochondrial dysfunction in Alzheimer's disease

AIMS: This study investigated the relationship between plasma Wnt2b levels and Alzheimer's disease (AD), and explored the effect of Wnt2b on mitochondrial dysfunction in AD. METHODS: Healthy and AD subjects, AD transgenic mice, and in vitro models were used to investigate the roles of Wnt2b in...

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Detalles Bibliográficos
Autores principales: Xu, Ling‐Zhi, Li, Bing‐Qiu, Li, Fang‐Yu, Quan, Mei‐Na, Qin, Wei, Li, Ying, Li, Wen‐Wen, Zhao, Yu, Wei, Yi‐Ping, Jia, Jian‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324363/
https://www.ncbi.nlm.nih.gov/pubmed/36852442
http://dx.doi.org/10.1111/cns.14139