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Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53‐ALOX15 signaling pathway

BACKGROUND: Spinal cord injury (SCI) is a highly disabling condition in spinal surgery that leads to neuronal damage and secondary inflammation. Ferroptosis is a non‐apoptotic type of cell death that has only recently been identified, which is marked primarily by iron‐dependent and lipid‐derived rea...

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Detalles Bibliográficos
Autores principales: Li, Dachuan, Lu, Xiao, Xu, Guangyu, Liu, Siyang, Gong, Zhaoyang, Lu, Feizhou, Xia, Xinlei, Jiang, Jianyuan, Wang, Hongli, Zou, Fei, Ma, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324365/
https://www.ncbi.nlm.nih.gov/pubmed/36942513
http://dx.doi.org/10.1111/cns.14150