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Effects of memantine on mania‐like phenotypes exhibited by Drosophila Shaker mutants

INTRODUCTION: Increased glutamate levels and electrolytic fluctuations have been observed in acutely manic patients. Despite some efficacy of the non‐competitive NMDA receptor antagonist memantine (Mem), such as antidepressant‐like and mood‐stabilizer drugs in clinical studies, its specific mechanis...

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Detalles Bibliográficos
Autores principales: Mocci, Ignazia, Casu, Maria Antonietta, Sogos, Valeria, Liscia, Anna, Angius, Rossella, Cadeddu, Francesca, Fanti, Maura, Muroni, Patrizia, Talani, Giuseppe, Diana, Andrea, Collu, Maria, Setzu, Maria Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324369/
https://www.ncbi.nlm.nih.gov/pubmed/36942502
http://dx.doi.org/10.1111/cns.14145