Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG

Antibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. The associative model presupposes that Fc receptors cannot discriminate antigen-bound IgG from free IgG in solution and have equivalent affinities for each....

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Detalles Bibliográficos
Autores principales: Crowley, Andrew R., Mehlenbacher, Matthew R., Sajadi, Mohammad M., DeVico, Anthony L., Lewis, George K., Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324447/
https://www.ncbi.nlm.nih.gov/pubmed/37405954
http://dx.doi.org/10.1080/19420862.2023.2231128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324447/
https://www.ncbi.nlm.nih.gov/pubmed/37405954
http://dx.doi.org/10.1080/19420862.2023.2231128

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